Consorzio Interuniversitario per lo sviluppo dei Sistemi a Grande Interfase
Center for Colloid and Surface Science
Center for Colloid and Surface Science
Position: Permanent Staff
Email: alessandra.stefan@unibo.it
Phone: 051 2093-718
Location: Bologna
Over-expression of recombinant proteins in Escherichia coli.
Purification and characterization of the diphtheria toxin variant CRM197.
Bacterial replication and DNA Polymerase III.
Antisense RNAs and bacterial silencing.
Plant protein hydrolysates.
July 1998: Master degree in Applied Genetics, University of Bologna, Italy (70 cum laude/70). Title: “Phosphoprotein 85 kDa (pp85) of human Herpesvirus 7 (HHV-7)”.
1998-1999: CSGI fellowship at the University of Bologna on “Development of water-in-oil macroemulsions sustain long-term viability of microbial cells”.
1995-2005: Studies and research activity at: Virology and Microbiology Laboratory, Dept. of Experimental Pathology (University of Bologna); Marjorie B. Kovler Viral Oncology Laboratories” (University of Chicago, Illinois, USA); Plant Molecular Biology Laboratory, IMBB (Heraklion, Crete, Greece).
2005: PhD in Applied Biocatalysis and Industrial Microbiology at the University of Bologna. Title: "Structural analysis of antisense RNAs involved in gene silencing in Escherichia coli". Advisor: Prof. A. Hochkoeppler (University of Bologna).
2006-present: Researcher at the Department of Industrial Chemistry and Materials of the University of Bologna.
Peptides inhibiting the assembly of monomeric human l-lactate dehydrogenase into catalytically active homotetramer decrease the synthesis of lactate in cultured cells
- Alessandra Stefan - Gentilucci L. - Ruffolo F. - Rossi V. - Sordi S. - He T. - di Stefano G. - Santino F. - Brigotti M. - Scotti C. - Iamele L. - de Jonge H. - Piaz F.D. - Santarcangelo D.R. - Alejandro HochkoepplerThe catalytic action of human D-lactate dehydrogenase is severely inhibited by oxalate and is impaired by mutations triggering D-lactate acidosis
- Alessandra Stefan - Mucchi A. - Alejandro HochkoepplerThe Mycobacterium tuberculosis protein tyrosine phosphatase MptpA features a pH dependent activity overlapping the bacterium sensitivity to acidic conditions
- Kovermann M. - Alessandra Stefan - Palazzetti C. - Immler F. - Dal Piaz F. - Bernardi L. - Cimone V. - Bellone M.L. - Alejandro HochkoepplerASFV DNA polymerase extends recessed DNAs with catalytic efficiencies outperforming those exerted on gapped DNA substrates
- Lapenna A. - Alessandra Stefan - Alejandro HochkoepplerUse of cotton textiles coated by ir(III) tetrazole complexes within ceramic silica nanophases for photo-induced self-marker and antibacterial application
- Zanoni I. - Blosi M. - Fiorini V. - Crosera M. - Ortelli S. - Stagni S. - Alessandra Stefan - Psilodimitrakopoulos S. - Stratakis E. - Filon F.L. - Costa A.L.Synthesis and Photochemical Properties of Manganese(I) Tricarbonyl Diimine Complexes Bound to Tetrazolato Ligands
- Stout M.J. - Alessandra Stefan - Skelton B.W. - Sobolev A.N. - Massi M. - Alejandro Hochkoeppler - Stagni S. - Simpson P.V.Substrate Activation of the Low-Molecular Weight Protein Tyrosine Phosphatase from Mycobacterium tuberculosis
- Alessandra Stefan - Dal Piaz F. - Girella A. - Alejandro HochkoepplerAntibacterial activity of a new class of tris homoleptic Ru (II)-complexes with alkyl-tetrazoles as diimine-type ligands
- Monti N. - Zacchini S. - Massi M. - Alejandro Hochkoeppler - Giorgini L. - Fiorini V. - Alessandra Stefan - Stagni S.Purification from Deinococcus radiodurans of a 66 kDa ABC transporter acting on peptides containing at least 3 amino acids
- Alessandra Stefan - Gentilucci L. - Piaz F.D. - D'Alessio F. - Santino F. - Alejandro HochkoepplerStructural and catalytic insights into HoLaMa, a derivative of Klenow DNA polymerase lacking the proofreading domain
- Kovermann M. - Alessandra Stefan - Castaldo A. - Caramia S. - Alejandro HochkoepplerConsorzio interuniversitario per lo sviluppo dei Sistemi a Grande Interfase
Department of Chemistry, University of Florence - Via della Lastruccia 3 50019 - Sesto Fiorentino (FI)
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