Consorzio Interuniversitario per lo sviluppo dei Sistemi a Grande Interfase
Center for Colloid and Surface Science

Personal information

Position: Post-Doc

Email: alessio.nocentini@unifi.it

Phone: +39 055 4573685

Location: Firenze


Fields of Interest and Expertise

Medicinal Chemistry Drug Design Organic Chemistry, Molecular Modelling, Enzymology

Teaching

Docente di Analisi dei Medicinali I – modulo II B030128 (B054) CdLM in Farmacia, Scuola di Scienze della salute umana

Curriculum Vitae

2014–2017 PhD cum laude in Area del Farmaco e Trattamenti Innovativi: Curriculum Scienze Farmaceutiche (Medicinal Chemistry), NEUROFARBA Department, University of Florence - PhD Supervisor: Prof. Paola Gratteri 2008–2014 MSc, 110/110 cum laude in Pharmaceutical Chemistry and Technology, Pharmacy, University of Florence CURRENT AND PREVIOUS POSITION 2023–present RTD-b (Assistant Professor, SSD CHIM/08), NEUROFARBA Department, University of Florence, Italy 2020–2023 RTD-a (Assistant Professor, SSD CHIM/08), NEUROFARBA Department, University of Florence, Italy 2017–2020 Postdoctoral research fellowships, Supervisor: Prof. Claudiu T. Supuran, Prof. Paola Gratteri, NEUROFARBA Department, University of Florence

Awards

Premio Miglior Tesi di Dottorato 2018, Divisione di Chimica Farmaceutica, Società Chimica Italiana

Unit

Publications

Synthesis and investigation of selective human carbonic anhydrase IX, XII inhibitors using coumarins bearing a sulfonamide or biotin moiety

- Begines P. - Bonardi A. - Giovannuzzi S. - Nocentini Alessio - Gratteri P. - De Luca V. - González-Bakker A. - Padrón J.M. - Clemente Capasso - Supuran C.T.
Chemico-Biological Interactions

Hydrogen Sulfide-Releasing Carbonic Anhydrase Inhibitors Effectively Suppress Cancer Cell Growth

- Bonardi A. - Nocentini Alessio - de Luca V. - Clemente Capasso - Elkaeed E.B. - Eldehna W.M. - Supuran C.T.
International Journal of Molecular Sciences

Development of Penicillin-Based Carbonic Anhydrase Inhibitors Targeting Multidrug-Resistant Neisseria gonorrhoeae

- Bonardi A. - Nocentini Alessio - Giovannuzzi S. - Paoletti N. - Ammara A. - Bua S. - Abutaleb N.S. - Abdelsattar A.S. - Clemente Capasso - Gratteri P. - Flaherty D.P. - Seleem M.N. - Supuran C.T.
Journal of Medicinal Chemistry

Leveraging SARS-CoV-2 Main Protease (Mpro) for COVID-19 Mitigation with Selenium-Based Inhibitors

- De Luca V. - Angeli A. - Nocentini Alessio - Gratteri P. - Pratesi S. - Tanini D. - Carginale V. - Capperucci A. - Supuran C.T. - Clemente Capasso
International journal of molecular sciences

CD73 Inhibitors as Antitumor Agents

- Clemente Capasso - Nocentini Alessio - Supuran C.T.
Topics in Medicinal Chemistry

Aryl derivatives of 3H-1,2-benzoxaphosphepine 2-oxides as inhibitors of cancer-related carbonic anhydrase isoforms IX and XII

- Balašova A. - Pustenko A. - Nocentini Alessio - Daniela Vullo - Supuran C.T. - Žalubovskis R.
Journal of Enzyme Inhibition and Medicinal Chemistry

Biochemical, structural, and computational studies of a γ-carbonic anhydrase from the pathogenic bacterium Burkholderia pseudomallei

- Di Fiore A. - De Luca V. - Langella E. - Nocentini Alessio - Buonanno M. - Monti S.M. - Supuran C.T. - Clemente Capasso - De Simone G.
Computational and Structural Biotechnology Journal

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